ENKORE

About this cluster

The Cluster on Endocrine Disrupting Chemicals and Knowledge on Health-related Effects (also known as ENKORE) was launched in 2024 (with €35 million in EU funding) and is composed of 5 projects selected under call HORIZON-HLTH-2023-ENVHLTH-02-03 of Horizon Europe:

The cluster is expected to continue its activities until 2028 and is working to improve and expand knowledge on the health impacts of endocrine disruptors, delivering the necessary tools to prevent and minimise exposure to these harmful chemicals and raise awareness of their harmful health effects.

Background

Endocrine-disrupting chemicals (EDCs) are substances that interfere with the normal functioning of the endocrine system, posing significant risks to human health and the environment. These chemicals, found in everyday products such as plastics, cosmetics, pesticides and industrial chemicals, are linked to a range of health issues, including reproductive disorders, developmental delays, metabolic diseases and certain cancers. EDCs also contribute to broader environmental challenges, affecting wildlife and entire ecosystems.

Despite decades of research, significant scientific uncertainties remain regarding the long-term impacts of exposure to EDCs, particularly at low doses and during critical periods of development. These uncertainties have hindered the development and implementation of effective policies to mitigate their risks.

The EU has played a pivotal role in advancing the understanding of EDCs and their effects. Key initiatives, such as the Chemicals Strategy for Sustainability and the European Green Deal, aim to reduce the presence of harmful chemicals in the environment and promote safer alternatives. Regulatory frameworks like REACH and the Biocidal Products Regulation have established stricter guidelines for the use and management of substances known to disrupt endocrine function.

Which EU priorities does this cluster contribute to?

Highlights

Brochure